Madonna admitted she was "too big of a p***y" to do drugs on her MOJO Magazine interview.
"My problem is I don't have the stamina to take drugs. I feel terrible afterwards. I'm destroyed for days and days. I can't do anything and I don't want that inconvenience in my life. So I don't feel it's worth the price you have to pay. That's me.
"Even when I was younger and in my 20s, trying this and that ... I mean, I never really did that many drugs. I'm too big of a p***y. Also, I'm a dancer and I don't want to destroy my body. I want to feel physically good.
"So it never came naturally to me to get out of my brains or get so high that I couldn't get out of bed for three days. And that's what happened to me if I did anything."
She added: "It's about how people take drugs to connect to God or to a higher level of consciousness. I keep saying, 'Plugging into the matrix'.
"If you get high, you can do that, which is why a lot of people drop acid or do drugs, because they want to get closer to God.
"But there's going to be a short circuit, and that’s the illusion of drugs, because they give you the illusion of getting closer to God, but ultimately they kill you."
"I mean, I tried everything once, but as soon as I was high, I spent my time drinking tons of water to get it out of my system. As soon as I was high, I was obsessed with flushing it out of me. I was like, Okay, I’m done now."